3D Hyaluronic Acid
Multi-layered function, precise effect – triple-structured hyaluronic acid for modern applications in cosmetics, functional foods and beverages, dietary supplements and medical products.
The triple-structured hyaluronic acid developed by Swiss Hyaluronic AG specifically combines three different molecular weight classes (high, medium, low) in a single formulation. This unique structure enables a multidimensional effect that is based on the natural distribution in human tissue – with benefits for moisture, elasticity, protection and regeneration.
Our active ingredient meets the highest requirements for companies in terms of functionality, stability and regulatory safety – ideal for complex applications in:
- Functional cosmetics
- Food supplements and nutraceutical products
- medical products and applications
- functional drinks and foods
Introduction
What makes our triple-structured hyaluronic acid special?
Classic hyaluronic acid formulations usually consist of molecules with a uniform molecular weight. These primarily have a superficial or locally limited effect.
The triple-structured variant, on the other hand, combines high-molecular, medium-molecular and low-molecular hyaluronic acid in a defined ratio. This creates complementary mechanisms of action that reinforce each other:
- High molecular weight (<>1,000 kDa / HA1): water binding, protective film, skin barrier
- Medium molecular weight (200–400 kDa / HA2): anti-inflammatory, structure-preserving
- Low molecular weight (50–70 kDa / HA3): deep-acting, cell-stimulating
This structure creates a multidimensional level of effectiveness comparable to natural distribution in human tissue – a decisive advantage in nutritional, cosmetic and therapeutic applications.
3D hyaluronic acid unfolds its potential both when applied externally and when taken orally, thereby contributing to the targeted support of key bodily functions.
Particularly relevant for concepts in the field of longevity
Thanks to its versatile effects on skin, tissue, joints and mucous membranes, it actively contributes to healthy ageing and maintaining quality of life.
Effect
Science-Backed Barrier Functions
The unique structure of our 3D hyaluronic acid supports four central protective mechanisms in the human body – scientifically validated and functionally effective. They act at cellular, molecular, and physical levels and are crucial for the integrity of skin, hair, nails, mucous membranes, joints, and tissues.
Biological Barrier
Stabilizes the microbiome, supports the function of probiotic cultures, and balances dysbiosis – ideal for products promoting gut health and immune balance.
Chemical Barrier
Forms a bioactive protective layer on mucous membranes (e.g., oral, intestinal, vaginal), reduces oxidative stress, and promotes the regeneration of epithelial tissues.
Mechanical Barrier
Improves the tightness of cell junctions (tight junctions), strengthens barrier tissues, and protects against uncontrolled permeability – e.g., in ‘leaky gut’ conditions.
Immune Barrier
Serves as a molecular signal (DAMP – Damage Associated Molecular Pattern) and specifically activates innate immune mechanisms to defend against pathogenic microorganisms.
Benefits
Comprehensive Benefits for Innovative Products
Six key benefits, one revolutionary formula. Our 3D hyaluronic acid unfolds its effects precisely and efficiently – at different levels and in various tissues. It is ideal for functional formulations in cosmetics, medicine, dietary supplements, as well as food and beverages.
Skin Hydration
The combination of all three hyaluronic acid types enables continuous and multi-layered water supply to the skin. The result: reduced transepidermal water loss (TEWL), a smoother complexion, and measurably improved hydration.
Skin Elasticity
Through deep-acting rehydration of the extracellular matrix, the skin’s biomechanical tension is strengthened – with positive effects on firmness and structure.
Anti-Aging Effect
Promotes fibroblast activity and supports collagen synthesis. Clinical studies show a reduction in fine wrinkles and improved skin density with regular use.
Synovial Fluid
Increases the viscoelastic properties of joint lubricant, protects cartilage structures from wear and tear, and improves joint mobility – especially under high stress or age-related volume loss.
Tissue Homeostasis
Stabilizes the balance between inflammatory and regenerative processes at the cellular level. This is particularly relevant for wound healing products, sensitive skin, or inflammatory conditions.
Lipid Barrier
Regenerates the natural skin protective layer and has a barrier-stabilizing effect on disturbed skin flora or increased environmental stress. Long-term use can demonstrably improve skin resistance.
Properties
Technical Properties
Maximum purity, production control, and application flexibility:
Triple-structured hyaluronic acid (HA1, HA2, HA3)
High purity (≥ 95%)
Produced by bio-fermentative processes (microbial, animal-free)
Vegan, halal, and GMO-free
GMP-compliant production
Free from preservatives, colorless and odorless
Stable in solution (even under thermal conditions)
Can be used orally and topically
Supported by current scientific publications
Availability: Supplied as bulk liquid (concentration: 10 mg/ml), individually fillable. Long-term stability due to buffered solution with natural preservative system (potassium sorbate). Shelf life ≥ 24 months.
Structure of Hyaluronic Acid
Structure of Hyaluronic Acid
Precise Composition for Optimal Efficacy
Classic hyaluronic acid with a uniform molecular weight often acts only superficially. In contrast, our triple-structured hyaluronic acid combines three defined molecular sizes, thus achieving a multi-dimensional level of action – comparable to the natural distribution in human tissue.
HA1 – High Molecular Weight (>1,000 kDa)
Binds moisture on the surface, protects cells from dehydration, forms a breathable film – ideal for skin, eye, and mucous membrane applications.
HA2 – Medium Molecular Weight (200–400 kDa)
Reduces inflammatory markers, sustainably strengthens tissue structure, and specifically supports regeneration in cases of irritation or structural instability.
HA3 – Low Molecular Weight (50–70 kDa)
Penetrates deep into the matrix, activates cellular repair processes, stimulates endogenous hyaluronic acid production, and improves tissue resilience.
Harness the potential of triple-structured hyaluronic acid for your high-quality product lines.
Swiss Hyaluronic supplies customized raw material solutions of pharmaceutical quality – as a functional component for dietary supplements, cosmetics, functional food, and medical applications.